Athlete’s foot, medically known as tinea pedis, is more than just a common fungal infection of the feet. For many individuals, it becomes a persistent, recurring condition that standard over-the-counter (OTC) treatments fail to resolve. Characterised by itchiness, scaling, burning, and cracked skin — often between the toes — athlete’s foot can severely affect comfort and mobility, especially for those with active lifestyles or underlying health conditions.

While most cases of athlete’s foot respond well to topical antifungals, chronic or severe infections may require more advanced interventions, including prescription medications and professional guidance. Clinics specialising in podiatry in Crawley and other parts of Australia have observed a growing number of cases where OTC products simply do not offer long-term relief, prompting the need for clinical evaluation and stronger solutions.
This article explores why athlete’s foot may become chronic, what prescription treatments are available, and how podiatrists can help eliminate the problem for good.
Understanding Athlete’s Foot
Athlete’s foot is caused primarily by dermatophyte fungi, which thrive in warm, moist environments such as locker rooms, public showers, swimming pools, and inside sweaty shoes. The condition is highly contagious and can spread via skin contact, towels, footwear, or even flooring surfaces.
Common symptoms include:
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Redness and flaking skin between the toes
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Persistent itching or burning sensation
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Cracked heels or peeling soles
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Foul odour from the affected foot
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Thickened or discoloured skin
If left untreated or if managed inadequately, the infection can spread to the toenails (onychomycosis), hands, or other body parts, leading to a more complex dermatological issue.
Why Athlete’s Foot Becomes Chronic
While many assume athlete’s foot is easily treated, several factors can cause it to become chronic:
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Incorrect Diagnosis
Other conditions like eczema, psoriasis or contact dermatitis can mimic athlete’s foot, leading to improper self-treatment. Misdiagnosis can delay effective care and worsen symptoms.
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Ineffective Treatment Use
Many individuals stop using antifungal creams too soon or fail to apply them consistently. Even after symptoms appear to subside, residual fungi may remain, causing recurrence.
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Underlying Health Conditions
Individuals with diabetes, compromised immune systems, or circulatory issues are at higher risk of chronic infections. Their bodies may not be able to fight off the fungal growth effectively.
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Environmental Factors
Wearing non-breathable footwear, poor foot hygiene, and exposure to contaminated surfaces can contribute to reinfection or prolong existing symptoms.
In such cases, a podiatrist may recommend prescription-strength antifungal agents or combination therapy to eliminate the root of the infection.
Prescription Options for Athlete’s Foot
For cases that do not respond to OTC treatments, a variety of prescription solutions are available. These may be topical or oral, depending on the severity and duration of the infection.
1. Topical Prescription Antifungals
Prescription-strength creams and gels often contain higher concentrations of active ingredients like terbinafine, econazole, or ciclopirox. These penetrate deeper into the skin and are more effective against stubborn fungal strains.
Common prescription topicals include:
These are usually applied once or twice daily for 2 to 4 weeks. In some cases, extended use may be necessary.
2. Oral Antifungals
For moderate to severe or widespread infections, oral antifungal medications may be prescribed. These work systemically and are particularly effective if the infection has spread to the nails or if topicals have failed.
Frequently prescribed oral antifungals include:
It’s important to note that oral antifungals can interact with other medications and may impact liver function. Therefore, blood tests and medical supervision are typically required during treatment.
3. Combination Therapy
In some cases, both topical and oral medications are used together. This dual approach ensures that the infection is addressed both at the surface and systemically, minimising the chance of recurrence.
According to DermNet NZ, combination therapy often leads to higher success rates, especially in chronic cases that resist single-modality treatment.

Role of Podiatrists in Managing Chronic Athlete’s Foot
Podiatrists play a crucial role in diagnosing and treating chronic athlete’s foot. They conduct a thorough clinical evaluation, which may include:
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Skin scrapings for laboratory testing (fungal cultures)
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Assessment of foot hygiene and footwear
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Identifying underlying health conditions that may be contributing to chronicity
Mid-treatment, they may adjust prescriptions based on patient response or suggest alternative solutions if the infection does not resolve.
Some advanced podiatry clinics in Crawley also utilise adjunct therapies such as laser treatment for fungal infections, which can offer relief when medication alone falls short.
Lifestyle Adjustments to Prevent Recurrence
Even the most effective prescription medications can be undermined if preventative measures are not taken. Individuals suffering from chronic athlete’s foot should adopt long-term hygiene and lifestyle changes, including:
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Wearing moisture-wicking socks: Materials like merino wool or synthetic fibres reduce sweat retention.
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Rotating shoes: Give shoes at least 24 hours to air out before reusing.
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Using antifungal powders or sprays: Apply inside shoes and on feet as a preventative measure.
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Washing feet daily: Dry thoroughly, especially between the toes.
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Avoiding walking barefoot in public spaces: Use shower shoes or flip-flops in gyms, pools, and locker rooms.
According to the Cleveland Clinic, consistent hygiene is one of the most effective tools for preventing athlete’s foot from recurring after treatment.
When to See a Podiatrist
It is advisable to consult a healthcare professional if:
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The infection persists beyond two weeks despite OTC treatment
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Symptoms worsen or spread
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The toenails become discoloured or thickened
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There is excessive pain, swelling, or pus (indicating a secondary bacterial infection)
A trained podiatrist will not only diagnose the exact cause but can also differentiate fungal infections from other skin conditions that may appear similar. This ensures the treatment plan is both targeted and effective.
Prescription Therapy: Addressing More Than the Surface
Chronic athlete’s foot can extend beyond surface-level discomfort. For individuals with underlying health conditions like diabetes or peripheral neuropathy, it poses a higher risk of complications such as ulcers or cellulitis. Prescription therapy tackles the deeper fungal colonies embedded within skin layers and provides long-term solutions when OTC products fall short.
Moreover, dermatological specialists and podiatrists may also explore fungal resistance if the infection proves unresponsive to multiple courses of treatment. This makes early professional intervention essential for chronic cases.
Latest Innovations in Antifungal Therapy
New research is continuously advancing the treatment options for fungal skin infections. The development of nanotechnology-based antifungal delivery systems, for example, aims to improve skin penetration and reduce resistance issues.
Similarly, studies are being conducted on photodynamic therapy and antimicrobial peptides, which could offer future alternatives to conventional treatments. Leading research institutions, including those referenced by ScienceDirect, are paving the way for more targeted and less invasive options.
Conclusion
Athlete’s foot may start as a minor irritation, but when left untreated or managed inadequately, it can evolve into a persistent and uncomfortable condition. Chronic athlete’s foot often signals the need for a stronger approach, including prescription antifungals, professional diagnosis, and comprehensive foot care strategies.
If standard treatments haven’t resolved the issue, seeking help from a podiatrist is not just beneficial — it’s essential. With expert guidance, prescription medications, and tailored prevention plans, chronic athlete’s foot can be effectively controlled and eventually eliminated.
For more detailed health information on fungal skin infections, visit trusted sources such as the Australian Institute of Health and Welfare or Healthdirect Australia.